You can literally become a bird and fly around Los Santos.
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You can literally become a bird and fly around Los Santos.

In the Enhanced version, eating a Peyote Plant transforms the player into a random animal — including birds that you can fly across the entire map using actual airplane controls, interacting with NPCs who react to you as if you're just another animal.

Source: Animals (GTA V) — CC BY-SA

The full story

Moo-ve over, Los Santos — Peyote Plants can turn you into a cow in the Enhanced version.
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Moo-ve over, Los Santos — Peyote Plants can turn you into a cow in the Enhanced version.

Peyote's not all cute and cuddly — cougar mode means even Trevor becomes prey.
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Peyote's not all cute and cuddly — cougar mode means even Trevor becomes prey.

Monkey business confirmed — NPCs have zero clue there's a player behind those beady eyes.
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Monkey business confirmed — NPCs have zero clue there's a player behind those beady eyes.